no code implementations • 20 Oct 2020 • Kerui Peng, Yana Safonova, Mikhail Shugay, Alice Popejoy, Oscar Rodriguez, Felix Breden, Petter Brodin, Amanda M. Burkhardt, Carlos Bustamante, Van-Mai Cao-Lormeau, Martin M. Corcoran, Darragh Duffy, Macarena Fuentes Guajardo, Ricardo Fujita, Victor Greiff, Vanessa D. Jonsson, Xiao Liu, Lluis Quintana-Murci, Maura Rossetti, Jianming Xie, Gur Yaari, Wei zhang, Malak S. Abedalthagafi, Khalid O. Adekoya, Rahaman A. Ahmed, Wei-Chiao Chang, Clive Gray, Yusuke Nakamura, William D. Lees, Purvesh Khatri, Houda Alachkar, Cathrine Scheepers, Corey T. Watson, Gunilla B. Karlsson Hedestam, Serghei Mangul
With the advent of high-throughput sequencing technologies, the fields of immunogenomics and adaptive immune receptor repertoire research are facing both opportunities and challenges.
1 code implementation • 25 Apr 2020 • Daniel Mas Montserrat, Arvind Kumar, Carlos Bustamante, Alexander Ioannidis
With declining sequencing costs a promising and affordable tool is emerging in cancer diagnostics: genomics.
Genomics Populations and Evolution
no code implementations • 22 Apr 2020 • Daniel Mas Montserrat, Carlos Bustamante, Alexander Ioannidis
Local-ancestry inference (LAI), also referred to as ancestry deconvolution, provides high-resolution ancestry estimation along the human genome.
1 code implementation • 27 Nov 2019 • Daniel Mas Montserrat, Carlos Bustamante, Alexander Ioannidis
Techniques to generate training samples that resemble real haploid sequences from ancestries of interest can be useful tools in such scenarios, since a generalized model can often be shared, but the unique human sample sequences cannot.
no code implementations • 6 Aug 2011 • John D. Chodera, Phillip Elms, Frank Noé, Bettina Keller, Christian M. Kaiser, Aaron Ewall-Wice, Susan Marqusee, Carlos Bustamante, Nina Singhal Hinrichs
Single-molecule force spectroscopy has proven to be a powerful tool for studying the kinetic behavior of biomolecules.
Statistical Mechanics Biological Physics Biomolecules