1 code implementation • 14 Sep 2023 • Tram Huynh, Zixuan Cang
Here, we present a tool, scGeom for exploiting the multiscale and multidimensional structures in scRNA-seq data by inspecting the geometry via graph curvature and topology via persistent homology of both cell networks and gene networks.
no code implementations • 31 May 2022 • Kathryn Dover, Zixuan Cang, Anna Ma, Qing Nie, Roman Vershynin
In general applications, other methods can be used for the alignment and dimension reduction modules.
no code implementations • 27 Aug 2017 • Zixuan Cang, Lin Mu, GuoWei Wei
This work introduces a number of algebraic topology approaches, such as multicomponent persistent homology, multi-level persistent homology and electrostatic persistence for the representation, characterization, and description of small molecules and biomolecular complexes.
no code implementations • 4 Oct 2015 • Zixuan Cang, Lin Mu, Kedi Wu, Kristopher Opron, Kelin Xia, Guo-Wei Wei
However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology.
Biomolecules