Search Results for author: Zixuan Cang

Found 4 papers, 1 papers with code

Topological and geometric analysis of cell states in single-cell transcriptomic data

1 code implementation14 Sep 2023 Tram Huynh, Zixuan Cang

Here, we present a tool, scGeom for exploiting the multiscale and multidimensional structures in scRNA-seq data by inspecting the geometry via graph curvature and topology via persistent homology of both cell networks and gene networks.

Clustering

AVIDA: Alternating method for Visualizing and Integrating Data

no code implementations31 May 2022 Kathryn Dover, Zixuan Cang, Anna Ma, Qing Nie, Roman Vershynin

In general applications, other methods can be used for the alignment and dimension reduction modules.

Dimensionality Reduction

Representability of algebraic topology for biomolecules in machine learning based scoring and virtual screening

no code implementations27 Aug 2017 Zixuan Cang, Lin Mu, GuoWei Wei

This work introduces a number of algebraic topology approaches, such as multicomponent persistent homology, multi-level persistent homology and electrostatic persistence for the representation, characterization, and description of small molecules and biomolecular complexes.

BIG-bench Machine Learning Descriptive

A topological approach for protein classification

no code implementations4 Oct 2015 Zixuan Cang, Lin Mu, Kedi Wu, Kristopher Opron, Kelin Xia, Guo-Wei Wei

However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology.

Biomolecules

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