1 code implementation • 28 Jul 2022 • Xiaomin Fang, Fan Wang, Lihang Liu, Jingzhou He, Dayong Lin, Yingfei Xiang, Xiaonan Zhang, Hua Wu, Hui Li, Le Song
Our proposed method, HelixFold-Single, first pre-trains a large-scale protein language model (PLM) with thousands of millions of primary sequences utilizing the self-supervised learning paradigm, which will be used as an alternative to MSAs for learning the co-evolution information.
1 code implementation • 12 Jul 2022 • Guoxia Wang, Xiaomin Fang, Zhihua Wu, Yiqun Liu, Yang Xue, Yingfei Xiang, dianhai yu, Fan Wang, Yanjun Ma
Due to the complex model architecture and large memory consumption, it requires lots of computational resources and time to implement the training and inference of AlphaFold2 from scratch.