no code implementations • 2 May 2023 • Ariel Nikas, Hasan Ahmed, Veronika I. Zarnitsyna
Heterogeneity in underlying susceptibility accelerates apparent waning, whereas heterogeneity in vaccine response slows down apparent waning.
no code implementations • 8 Feb 2023 • Ariel Nikas, Hasan Ahmed, Mie R. Moore, Veronika I. Zarnitsyna, Rustom Antia
We consider and computationally model mechanisms by which humoral memory present at baseline might instead increase infection load; we refer to this effect as EI-HM (enhancement of infection by humoral memory).
no code implementations • 24 May 2022 • Ariel Nikas, Hasan Ahmed, Veronika I. Zarnitsyna
We propose an extension of the Cox model based on including a time-vaccine interaction term with further optimization of partitioning time.
no code implementations • 3 Nov 2021 • William Waites, Matteo Cavaliere, Vincent Danos, Ruchira Datta, Rosalind M. Eggo, Timothy B. Hallett, David Manheim, Jasmina Panovska-Griffiths, Timothy W. Russell, Veronika I. Zarnitsyna
Transmission models for infectious diseases are typically formulated in terms of dynamics between individuals or groups with processes such as disease progression or recovery for each individual captured phenomenologically, without reference to underlying biological processes.