no code implementations • 13 Mar 2024 • Michael Phillips, Giuseppe Tronci, Christopher M. Pask, Stephen J. Russell
The nonwoven reinforced PGSLPA hydrogels exhibited a 60 % increase in compressive strength and an 80 % increase in elastic moduli compared to fibre-free PGSLPA samples.
no code implementations • 15 Dec 2021 • He Liang, Jie Yin, Kenny Man, Xuebin B. Yang, Elena Calciolari, Nikolaos Donos, Stephen J. Russell, David J. Wood, Giuseppe Tronci
The fast degradation of collagen-based membranes in the biological environment remains a critical challenge, resulting in underperforming Guided Bone Regeneration (GBR) therapy leading to compromised clinical results.
no code implementations • 5 Jan 2021 • Robabeh Gharaei, Giuseppe Tronci, Parikshit Goswami, Robert P. Wynn Davies, Jennifer Kirkham, Stephen J. Russell
The encapsulation of SAP in a nonwoven system with apatite-forming as well as localised and long-term SAP delivery capabilities is appealing as a potential means of achieving cost-effective bone repair therapy for critical size defects.
no code implementations • 5 Jan 2021 • Heather E. Owston, Katrina M. Moisley, Giuseppe Tronci, Stephen J. Russell, Peter V. Giannoudis, Elena Jones
Additional to the PL absorption and release capabilities needed for MSC attraction and growth, PCL3%-E also provided a favourable surface for the proliferation and alignment of periosteum- and bone marrow derived-MSCs, whilst possessing a barrier function to cell migration.
no code implementations • 5 Jan 2021 • M. Tarik Arafat, Giuseppe Tronci, David J. Wood, Stephen J. Russell
The design of antibacterial-releasing coatings or wrapping materials with controlled drug release capability is a promising strategy to minimise risks of infection and medical device failure in vivo.