no code implementations • 6 Nov 2023 • Blair Colyer, Maciej Bak, David Basanta, Robert Noble
Spatial agent-based models are increasingly used to investigate the evolution of solid tumours subject to localised cell-cell interactions and microenvironmental heterogeneity.
1 code implementation • 18 Jan 2023 • Maciej Bak, Blair Colyer, Veselin Manojlović, Robert Noble
Here we present warlock, an open-source automated computational workflow for fast, efficient simulation of intratumour population genetics in any of a diverse set of spatial structures.
no code implementations • 18 Oct 2022 • Jeffrey West, Fred Adler, Jill Gallaher, Maximilian Strobl, Renee Brady-Nicholls, Joel S. Brown, Mark Robertson-Tessi, Eunjung Kim, Robert Noble, Yannick Viossat, David Basanta, Alexander R. A. Anderson
In the previous few decades, experimental and clinical investigation of adaptive therapy has progressed synergistically with mathematical and computational modeling.