1 code implementation • 11 Oct 2021 • Hengrui Cai, Wenbin Lu, Rachel Marceau West, Devan V. Mehrotra, Lingkang Huang
In this paper, we present an optimal subgroup selection rule (SSR) that maximizes the number of selected patients, and in the meantime, achieves the pre-specified clinically meaningful mean outcome, such as the average treatment effect.
1 code implementation • 28 Apr 2020 • Devan V. Mehrotra, Rachel Marceau West
Randomized clinical trials are often designed to assess whether a test treatment prolongs survival relative to a control treatment.