no code implementations • 11 Jan 2021 • Apostolos Gkatzionis, Stephen Burgess, Paul J. Newcombe
Mendelian randomization is the use of genetic variants to assess the existence of a causal relationship between a risk factor and an outcome of interest.
1 code implementation • 25 Jul 2020 • Andrew Yiu, Robert J. B. Goudie, Stephen J. Sharp, Paul J. Newcombe, Brian D. M. Tom
Weighted Cox regression is the most widely used approach for analysing case-cohort data within the Cox model, but is inefficient.
Methodology Applications
no code implementations • 25 Apr 2020 • Jixiong Wang, Ashish Patel, James M. S. Wason, Paul J. Newcombe
High-dimensional biomarkers such as genomics are increasingly being measured in randomized clinical trials.