The Cell Physiome: What do we need in a computational physiology framework for predicting single cell biology?

no code implementations • 27 Feb 2022 • Vijay Rajagopal, Senthil Arumugam, Peter Hunter, Afshin Khadangi, Joshua Chung, Michael Pan

We present the motivation for the Cell Physiome: a framework and approach for creating, sharing, and using biophysics-based computational models of single cell physiology.

Network Thermodynamical Modelling of Bioelectrical Systems: A Bond Graph Approach

1 code implementation • 4 Sep 2020 • Peter J. Gawthrop, Michael Pan

Interactions between biomolecules, electrons and protons are essential to many fundamental processes sustaining life.

A thermodynamic framework for modelling membrane transporters

1 code implementation • 12 Jun 2018 • Michael Pan, Peter J. Gawthrop, Kenneth Tran, Joseph Cursons, Edmund J. Crampin

Membrane transporters contribute to the regulation of the internal environment of cells by translocating substrates across cell membranes.

Biomolecules