Search Results for author: Macoto Kikuchi

Found 5 papers, 1 papers with code

Phenotype selection due to mutational robustness

no code implementations24 Oct 2023 Macoto Kikuchi

Darwinian evolution gives rise not only to the adaptation to the environment but also to the enhancement of the robustness against mutation.

Selection bias

Evolution enhances mutational robustness and suppresses the emergence of a new phenotype: A new computational approach for studying evolution

no code implementations5 Dec 2020 Tadamune Kaneko, Macoto Kikuchi

In this study, we used the multicanonical Monte Carlo method developed in statistical physics to construct a reference ensemble of GRNs and compared it with the outcomes of ES.

Emergence of cooperative bistability and robustness of gene regulatory networks

no code implementations28 Jul 2019 Shintaro Nagata, Macoto Kikuchi

As a result, the following properties were found: (1) Highly-fit GRNs exhibited bistability for intermediate input between "on" and "off".

The interplay of intrinsic disorder and macromolecular crowding on α-synuclein fibril formation

no code implementations12 Nov 2014 Nobu C. Shirai, Macoto Kikuchi

In order to investigate the coupled effect of the intrinsic disorder of {\alpha}-syn and macromolecular crowding, we construct a lattice gas model of {\alpha}-syn in contact with a crowding agent reservoir based on statistical mechanics.

Multi-Spin Coding of the Monte Carlo Simulation of the Three-State Random Potts Model and the Block-Spin Transformation

1 code implementation29 Jan 1996 Macoto Kikuchi, Yutaka Okabe

The multi-spin coding of the Monte Carlo simulation of the three-state Potts model on the simple cubic lattice is presented.

cond-mat

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