DDoS: A Graph Neural Network based Drug Synergy Prediction Algorithm

1 code implementation • 3 Oct 2022 • Kyriakos Schwarz, Alicia Pliego-Mendieta, Amina Mollaysa, Lara Planas-Paz, Chantal Pauli, Ahmed Allam, Michael Krauthammer

In contrast to conventional models relying on pre-computed chemical features, our GNN-based approach learns task-specific drug representations directly from the graph structure of the drugs, providing superior performance in predicting drug synergies.

Graph Neural Network