no code implementations • 13 Feb 2024 • Simon F. Martina-Perez, Isaac B. Breinyn, Daniel J. Cohen, Ruth E. Baker
Epithelial monolayers are some of the best-studied models for collective cell migration due to their abundance in multicellular systems and their tractability.
1 code implementation • 16 Jan 2024 • Carles Falcó, Daniel J. Cohen, José A. Carrillo, Ruth E. Baker
Finally, we compare our mathematical model predictions to different experiments studying cell cycle regulation and present a quantitative analysis on the impact of density-dependent regulation on cell migration patterns.
1 code implementation • 4 Sep 2023 • Yue Liu, Kevin Suh, Philip K. Maini, Daniel J. Cohen, Ruth E. Baker
When employing mechanistic models to study biological phenomena, practical parameter identifiability is important for making accurate predictions across wide range of unseen scenarios, as well as for understanding the underlying mechanisms.
1 code implementation • 6 Feb 2023 • Carles Falcó, Daniel J. Cohen, José A. Carrillo, Ruth E. Baker
Although tissues are usually studied in isolation, this situation rarely occurs in biology, as cells, tissues, and organs, coexist and interact across scales to determine both shape and function.