Exact solution of stochastic gene expression models with bursting, cell cycle and replication dynamics

1 code implementation • 9 Dec 2019 • Casper H. L. Beentjes, Ruben Perez-Carrasco, Ramon Grima

We show that protein distributions are well approximated by the solution of implicit models (a negative binomial) when the mean number of mRNAs produced per cycle is low and the cell cycle length variability is large.