no code implementations • 22 May 2024 • Ibrahim Isik, Mitra Rezaei, Adam Noel
System variations are considered with a higher spheroid porosity (i. e., with a higher effective diffusion coefficient) and with molecule uptake by the spheroid cells (approximated as a first-order degradation reaction while molecules diffuse within the spheroid).
no code implementations • 10 May 2023 • Ibrahim Isik, Hamidreza Arjmandi, Christophe Corre, Adam Noel
In this paper, a biophysical model is proposed that incorporates droplet soaking, diffusion of molecules within agar, cell growth over an agar surface, and absorption of signaling molecules by cells.
no code implementations • 1 Dec 2018 • Yuting Fang, Adam Noel, Andrew W. Eckford, Nan Yang
The number of molecules observed at each randomly-distributed bacterium is first derived by characterizing the diffusion and degradation of signaling molecules within the population.